Rencontres Inria et LJLL en calcul scientifique
- Date : 20/02/2017
- Place : 2 rue Simone Iff (ou: 41 rue du Charolais) - Salle Lions 1, bâtiment C - 11h00
- Guest(s) : Christian Scheider (Université de Vienne)
Bistability of lamellipodial fragments
In experiments bistability of lamellipodial fragments has been observed with perturbation induced switching between a nonpolarized-nonmoving and a polarized-moving state.
The Filament Based Lamellipodium Model, a two-dimensional, anisotropic, two-phase model of the lamellipodium is used to explain the bistability as a phenomenon induced by actin-myosin interaction.
The bistability is obtained both analytically in a strongly simplified model, and numerically in simulations of the full model.