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REO Research team

Numerical simulation of biological flows

  • Leader : Miguel Ángel Fernández
  • Research center(s) : CRI de Paris
  • Field : Digital Health, Biology and Earth
  • Theme : Modeling and Control for Life Sciences
  • Partner(s) : Sorbonne Université (UPMC),CNRS
  • Collaborator(s) : SORBONNE UNIVERSITE, CNRS

Team presentation

REO project-team is working on the numerical simulation of biological flows and cardiac electrophysiology. Its main objectives are:

  • the modeling of blood flow in large vessels, air flow in the respiratory tract, and the cardiac electrophysiology
  • the design and the analysis of efficient and robust numerical methods for these problems
  • the development of numerical software to assist medical decisions and to contribute to the design of medical devices.

REO put a strong effort in working with real data, coming either from clinicians or industrial partners. The development of methods for the interaction of data and simulation is therefore an important aspect of the activity of the team.

The team is bi-located at Inria Paris (near Gare de Lyon, Paris 12ème) and the Jacques-Louis Lions laboratory of University Pierre and Marie Curie (Sorbonne Universités UPMC Paris 6). It is made of about 20 people, including 9 permanent researchers (6 from INRIA, 1 from CNRS, 2 assistant-professors from UPMC)

Research themes

Direct and inverse modeling and computational methods for

  • blood flow and fluid-structure interaction problems: interaction blood / arteries or cardiac valves
  • cardiac electrophysiology and electromechanical coupling
  • air flow aerosol deposition in the respiratory tract

International and industrial relations

  • Current grants:
    • Joint Laboratory (ANR LabCom) CardioXcomp with the company Notocord (modeling of the electric activity of cardiac stem cells)
    • ANR project iFlow (liver hemodynamic)
    • FP7 European project REVAMMAD (retinal vascular modeling)
    • ANR project ExiFSI (fluid-structure interaction)
    • Transatlantic Leducq grant (congenital heart desease)
  • Former grants:
    • European project FP7-euHeart (personalized modeling of the heart)
    • ANR project "M3RS" (respiration)
    • Associated team "cardio" with Stanford and UCSD (computational hemodynamics)
    • ANR project "Endocom" (medical device for aneurysms)
    • Cardio3BioSciences
    • Cardiatis
    • ELA Medical
    • Projet européen FP5-RTN Haemodel
    • Associated team ACE
    • Air Liquide (in the framework of the network RNTS R-MOD).

Keywords: Scientific computing Numerical analysis Computational biomechanics Cardiovascular system Cardiac electrophysiology Respiratory system Fluid-structure interaction