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MODEMIC Research team

Modelling and Optimisation of the Dynamics of Ecosystems with MICro-organisme

  • Leader : Alain Rapaport
  • Research center(s) : CRI Sophia Antipolis - Méditerranée
  • Field : Digital Health, Biology and Earth
  • Theme : Modeling and Control for Life Sciences
  • Partner(s) : INRA
  • Collaborator(s) : INRA, SUPAGRO MONTPELLIER

Team presentation

The research activities of MODEMIC focus on modelling and simulating of natural or reconstituted microbial ecosystems, over several time and space scales, as well as various diversity levels. The main objectives of the project are:
  • a better understanding of microbial ecology, especially its functions (degradation, fermentation, sequestration...), its biodiversity and its role in preserving the environment (quality of water resources, soil fertility...)
  • new decision-making tools for managing and improving bioprocesses (decontamination, green chemistry...)
Applications are conducted with close collaborations with biologists, microbiologists and agronomists.

Research themes

  • Modelling and simulating microbial ecosystems:
    • macroscopic approach
    • microscopic approach
    • marriage of both approaches
  • Interpreting and analyzing experimental observations:
    • assessment of community structures
    • characterization of the interactions
    • observation of spatial structures
  • Controlling and optimizing bioprocesses:
    • identification, software sensors and filtering
    • bioprocess stabilization
    • optimal control of bioreactors
    • plant design and optimization

International and industrial relations

  • UMR Centro de Modelamiento Matematico, Santiago, Chile
  • Departamento de Ingeniera Matematica, Universidad de Chile, Santiago, Chile
  • Departamento de Matematica, Universidad Tecnica Federico Santa Maria, Valparaiso, Chile
  • Departamento de Ingenieria Informatica, Universidad de Santiago, Chile
  • Instituto de Matematica y Ciencias Afines, Universidad Nacional de Ingenieria - Lima, Peru
  • Centre for systems engineering and applied mechanics, Université catholique de Louvain-la-Neuve, Belgium
  • Automatic Control Laboratory, Université de Mons, Belgium
  • Departamento de Matematica Aplicada, University Complutense of Madrid, Spain
  • NRC Biotechnology Research Institute, Montréal, Canada
  • Probability and Statistics Group, School of Mathematics, University of Manchester, United Kingdom
  • Community and Conservation Ecology group, University of Groningen, Netherland
  • Department of Biology, McGill University, Montréal, Canada
  • School of Biology, Georgia Institute of Technology, Atlanta, USA
  • Laboratoire de Modélisation Mathématique et Numérique dans les Sciences de l'Ingénieur, Ecole Nationale d'Ingénieurs de Tunis, Université Tunis El-Manar, Tunisia
  • Laboratoire d'Automatique, Université de Tlemcen, Algeria
  • Laboratorio di Ingegneria Ambientale, Politecnico de Milano, Italy
  • Centre de Biotechnologie de Sfax, Tunisia
  • Grupo de Ingenieria Ambiental y Bioprocesos, Universidade de Santiago de Compostela, Spain
  • Escuela de Ingenieria Bioquimica, Pontifica Universidad Catholica de Valparaiso, Chile
  • Keywords: Modelling Microbial ecology Environment preservation Biodiversity Dynamical systems Optimisation Individual-based models Spatio-temporal dynamics Multi-scale Numerical simulations