The Dracula team develops mathematical and computational tools, methods and approaches for multiscale modeling of biological processes. The aim is to describe processes involving interactions between molecular and cellular dynamics, with consequences on the fate of cell populations (e.g., death, proliferation, differentiation) and biological tissues, while accounting for the inherent stochasticity of most physiological processes. The main biological applications deal with the development of blood cells (white and red blood cells, platelets) and the treatment of leukemia, immune responses optimization and vaccine design, prion and Alzheimer's diseases, slowly proliferating cell renewal (e.g., cardiac cells, neurons). Dracula is a joint Inria-CNRS (ICJ UMR 5208 and LBMC UMR 5239) research team.
In partnership with
Université Claude Bernard (Lyon 1),CNRS
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