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Innovative Computational Tools for Comparative Metagenomics

Jean-Michel Prima (*) - 6/02/2019

Analyzing plankton genomic distribution in seawater samples could provide valuable information on marine stock and help assess the impact of climate change on this biomass. But in those samples, microbial flora is sequenced without prior DNA separation among individuals. It is like not one, but myriad jigsaw puzzles whose pieces have been inadvertently mixed up in the same box. Comparing these pieces one to another and assembling them properly remains an elusive prospect for lack of adequate software. Funded by French research agency ANR and led by Inria research team GenScale, the HydroGen project has come up with a pair of new tools that will help biologists make sense of the data.

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