Team presentation

The aim of the project MODBIO is to develop computational models for molecular and cell biology. We are interested in two types of problems:

• Determining the structure of biological macromolecules,
• Discovering and understanding the function of biological systems.

We approach these questions by combining techniques from constraint programming, discrete optimization, hybrid systems, and statistical learning theory.

Research themes

• Determination and analysis of macromolecular envelops
• RNA structure and alternative splicing
• Predicting protein secondary structure
• Modeling biological systems with constraint programming

International and industrial relations

• Participation in the "Génopole Strasbourg Alsace Lorraine"

• Participation in the Bioinformatics Project of the region "Lorraine"

• Participation in the ARC INRIA "Process calculi and molecular networks"

• Participation in the LISCOS project of the European Community;

• Various national and international collaborations:

  • Laboratoire MAEM (Maturation des ARN et Enzymologie Moléculaire), Nancy

  • Laboratoire de Cristallographie LCM3B, Nancy;

  • Institut de Biologie et de Chimie des Protéines, Univ. Claude Bernard, Lyon

  • Institute of Mathematical Problems in Biology, Russian Academy of Sciences

  • University of California, Irvine, USA.