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Conference
International conference “Chance at the heart of the cell”
The conference “Chance at the heart of the cell” on stochastic gene expression from an experimental, theoretical and philosophical perspective will be held in Lyon on November 21, 22 and 23, 2011.
- Date : 21/11/2011 to 23/11/2011
- Place : Campus Lyon La Doua, Bâtiment INSA Lyon "La Rotonde", 16 rue des arts
- Organisers : Olivier Gandrillon (CGPHIMC - CNRS - University of Lyon, IXXI, Inria équipe DRACULA); Jean-Jacques Kupiec (Centre Cavaillès - Ecole Normale Supérieure - Paris); Delphine Kolesnik ( Institut d’histoire de la pensée classique - CERPHI UMR 5037- ENS Lyon); Guillaume Beslon ( INSA de Lyon, IXXI, Inria équipe BEAGLE)
The emergence of stochastic gene expression therefore raises important questions about its implications not only for biological theories but also about its epistemological status. This conference brought together experimental and theoretical biologists, modelers, epistemologists and philosophers to bring a new theoretical and epistemological dimension for research in this multidisciplinary field and create a unique opportunity for interaction between participants.
The following topics will be addressed by specialists:
Philosophy:
- Overview of determinism and probabilism
- What is chance?
- Objective and subjective probability
- Determinism in biology (from an historical and philosophical perspective)
- The example of physics (probability and indeterminism in statistical and quantum physics)
- Sociological and epistemological obstacles to probabilism in Biology
Biology:
- Overview of stochastic gene expression
- What are the causes of stochastic expression (diffusion of molecules, chromatin effects, etc.)
- Does stochastic gene expression contradict the genetic programming theory?
- The role of stochastic gene expression in cell differentiation and embryo development
- The modelization of stochastic gene expression and stochastic cell differentiation
- The role of stochastic gene expression in cancer
This meeting will be followed by an “Atelier d’approfondissement des questions ouvertes” (in french only), that will be organized on the 23 of September
Further reading
