Séminaire : CONTRAINTES

Modeling Organogenesis: Scaling Development from Stem Cells to Organs

Entrée libre.

Horaire : 10 h 30

  • Date : 28/03/2011
  • Lieu : Inria Rocquencourt, Bâtiment 8
  • Intervenants : Yaakov SETTY
  • Organisateurs : CONTRAINTES

In recent years, we have used software engineering tools to develop reactive models to simulate and analyze the development of organs. The
modeled systems embody highly complex and dynamic processes, by which a set of precursor stem cells proliferate, differentiate and move, to
form a functioning tissue. Three organs from diverse evolutionary organisms have been thus modeled: the mouse pancreas, the C. elegans
gonad, and partial rodent brain development. Analysis and execution of the models provided dynamic representation of the development,
anticipated known experimental results and proposed novel testable predictions. In my talk, I will l discuss challenges, goals and
achievement in this direction in science.

Mots-clés : Séminaire Paris - Rocquencourt CONTRAINTES

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